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Antidepressants (SSRIs)

Pet toxin reference — educational information only.
Pet toxins

What to know

Antidepressants (SSRIs) — toxicity in dogs and cats

EmergencyApplies to: dogs and cats.

Overview

Antidepressant medications - including SSRIs like fluoxetine (Prozac), sertraline (Zoloft), escitalopram (Lexapro), and SNRIs like venlafaxine (Effexor) - are among the top ten pet toxins reported to poison control every year. Dogs commonly ingest these medications by chewing through pill bottles or eating dropped tablets. Antidepressant poisoning in pets can cause a dangerous condition called serotonin syndrome, which involves agitation, elevated body temperature, tremors, seizures, and cardiac abnormalities. Effexor (venlafaxine) is particularly attractive to cats, who seem drawn to the capsule coating.

Symptoms

Agitation, tremors, seizures, elevated heart rate, vomiting

Typical onset

1-6 hours

What to do

Seek emergency care. Serotonin syndrome can be life-threatening.

This page is educational and does not replace veterinary advice. If your pet may have been exposed, call UVEC at (801) 218-2227 or ASPCA Poison Control at (888) 426-4435.

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Antidepressant medications - including SSRIs like fluoxetine (Prozac), sertraline (Zoloft), escitalopram (Lexapro), and SNRIs like venlafaxine (Effexor) - are among the top ten pet toxins reported to poison control every year. Dogs commonly ingest these medications by chewing through pill bottles or eating dropped tablets. Antidepressant poisoning in pets can cause a dangerous condition called serotonin syndrome, which involves agitation, elevated body temperature, tremors, seizures, and cardiac abnormalities. Effexor (venlafaxine) is particularly attractive to cats, who seem drawn to the capsule coating.

Symptoms
Agitation, tremors, seizures, elevated heart rate, vomiting
Onset
1-6 hours
What to do now
Seek emergency care. Serotonin syndrome can be life-threatening.
Call UVEC now: (801) 218-2227
This tool is informational only and does not replace veterinary advice. If ingestion may have happened, contact UVEC at (801) 218-2227 or ASPCA Poison Control at (888) 426-4435.